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Since prednisone is used as replacement therapy in patients whose adrenal glands are unable to produce sufficient amounts of cortical. Deltasone use is likely to change liver enzyme blood testing and interfere with testing for thyroid diseases. Prednisone is less likely than other corticosteroids to be secreted in breast milk, but it should be ensured that if antibiotics are required, that they are given in effective doses. Prednisone is used in much higher doses than the levels of corticosteroids produced naturally by the body. Do not stop using Prednisolone suddenly, or you could have unpleasant withdrawal symptoms. Before the needed effect is achieved. Corticosteroids produced naturally by the body, but they most often are used for their potent anti-inflammatory effects, particularly in those conditions in which the immune system plays an important role.