Nexium is usually taken once a day at least one hour before a meal. There are no restrictions on food, beverages, or activities while taking Nexium, unless otherwise directed by your doctor. Esomeprazole works best if taken on an empty stomach at least one hour before meals, swallowed whole and shouldn't be crushed or chewed. Nexium capsules should be taken at least one hour before meals, swallowed whole and shouldn't be crushed or chewed. Because Nexium is likely to appear in breast milk you will need to take Nexium. Decreasing stomach acid can help ulcers to heal and reflux, or heartburn symptoms to subside. Nexium is a type of medicine known as an acid pump inhibitor which works by decreasing the acid produced by acid pumps. Decreasing the acid produced by acid pumps.
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